about our clinical trials

Each study is unique with a specific set of parameters, including length of study, type of medication, and volunteer requirements.

We find volunteers through our extensive database and other recruitment strategies. MedVadis Research maintains an active relationship with volunteers throughout the clinical trial process to ensure compliance. Volunteers are encouraged to write daily diary entries, attend regular office visits, and have frequent telephone check-ins with staff, among other activities. Each volunteer’s progression is thoroughly documented, which enables the Food and Drug Administration (FDA) to reconstruct any study in case of an inspection. Our thorough procedures mitigate a placebo response in the randomized, double-blind, placebo-controlled studies we conduct.

Currently we are working on treating migraine and chronic pain with monoclonal antibodies against calcitonin gene-related peptide (CGRP) and nerve growth factor (NGF), respectively.

Our studies are ongoing and we encourage interested volunteers to inquire.

FAQs

Do volunteers get paid?

MedVadis Research at Boston PainCare conducts clinical trials on a wide range of medical conditions. Studies are unique and vary in length, medication or device treatment offered, and participation requirements. Volunteers for our studies come from our large subject database, our affiliated clinics, and recruitment campaigns conducted by our recruitment team. Each of our studies are conducted under the direct supervision of our physician investigators.

Why should I participate in a research study?

Research volunteers participate in clinical studies for a variety of reasons. The desire to help others by helping to bring new treatments to the market is one of the most common reasons cited by those participating in our studies. Other benefits include gaining access to treatments not yet available to the general public; undergoing comprehensive medical evaluations (that often includes physical examinations, imaging studies, ECGs, and laboratory work) at no cost; and working with physicians who have expertise in the conditions being studied.  

Is participating in a clinical trial dangerous?

Clinical research trials frequently involve treatments that either have yet to receive approval by the Food and Drug Administration (FDA) or have received approval for one or more indications and are now being studied for use in other medical conditions. As part of these investigations, both treatment effectiveness and side effects are examined. Study volunteers work closely with our physician investigators whose first and foremost responsibility is the protection of our study participants health and wellbeing. Furthermore, all of our studies must undergo extensive review by a safety committee (known as the Institutional Review Board or IRB) prior to study start. The IRB, as well as the study sponsor, monitors safety data throughout the course of each study in the interest of protecting the rights and welfare of each study volunteer.

What is a research sponsor?

A sponsor is the company or organization that provides the protocols, medications, and financing needed to carry out the study.

What is a study protocol?

A study protocol is the document that describes the reasons why a study is being conducted, the study’s objectives, and the methods to be used when carrying out the clinical trial. MedVadis uses the information contained in the study protocol to conduct each trial in a scientifically valid and safe manner.

How long do the clinical trials last?

Clinical trials vary in length depending upon the treatment and condition being studied. Typically, most studies range from several weeks to a year in length. However trials involving progressive conditions such as Alzheimer’s disease can last longer.

How long is each study visit?

Initial evaluations are typically 2-3 hours in length during which time education regarding the study is provided, informed consent is obtained, and a comprehensive medical evaluation is performed. Subsequent visits are usually shorter and typically take only about an hour.

How frequent are the study visits?

Office visits are usually monthly but can range from weekly to quarterly. Telephone or telehealth visits may also occur during a study.

Will I need to stay overnight?

While MedVadis does conduct some studies that require overnight stays, the majority of our trials do not.

Can I withdraw before a trial ends?

Obtaining the information needed to determine whether a treatment should be approved for general use depends upon the completion of study treatment by the majority of enrolled participants. With that said, participation in a clinical research trial is always voluntary and study participants can withdraw from a trial at any time.

Will I receive compensation for participating in a research trial?

Sponsors provide research volunteers compensation for their time and travel associated with the study. Some study sponsors will also provide transportation to and from study appointments.

Will I receive medical care from MedVadis during the study?

MedVadis is a research center that conducts research trials according to the protocols established by the sponsors. Volunteers gain valuable information regarding their overall health from the comprehensive assessments performed during the study, however, medical treatments unrelated to the clinical trials are not provided. Your primary care physician and/or other physician specialists will need to provide any treatments needed beyond those offered in the study. With your permission, MedVadis will share health information with your physicians to facilitate your healthcare treatment.

What if I would like to volunteer but there isn’t a trial that I qualify for?

MedVadis continually evaluates and launches new research projects. Please fill out our contact information form and our staff will reach out to you when a trial relevant to your interests becomes available. Your information will only be used by MedVadis and will never be shared with others.

Where are you located?

MedVadis is located at Boston PainCare, 85 First Avenue, Waltham MA 02451. We are conveniently located just off route 128 and have ample free parking.

Is your office handicap accessible?

Yes, our office is wheelchair accessible. There is handicap parking adjacent to the main entrance.

What is a study protocol?

A study protocol is the document that describes the reasons why a study is being conducted, the study’s objectives, and the methods to be used when carrying out the clinical trial. MedVadis uses the information contained in the study protocol to conduct each trial in a scientifically valid and safe manner.

FAQs

Do volunteers get paid?

MedVadis Research at Boston PainCare conducts clinical trials on a wide range of medical conditions. Studies are unique and vary in length, medication or device treatment offered, and participation requirements. Volunteers for our studies come from our large subject database, our affiliated clinics, and recruitment campaigns conducted by our recruitment team. Each of our studies are conducted under the direct supervision of our physician investigators.

Why should I participate in a research study?

Research volunteers participate in clinical studies for a variety of reasons. The desire to help others by helping to bring new treatments to the market is one of the most common reasons cited by those participating in our studies. Other benefits include gaining access to treatments not yet available to the general public; undergoing comprehensive medical evaluations (that often includes physical examinations, imaging studies, ECGs, and laboratory work) at no cost; and working with physicians who have expertise in the conditions being studied.  

Is participating in a clinical trial dangerous?

Clinical research trials frequently involve treatments that either have yet to receive approval by the Food and Drug Administration (FDA) or have received approval for one or more indications and are now being studied for use in other medical conditions. As part of these investigations, both treatment effectiveness and side effects are examined. Study volunteers work closely with our physician investigators whose first and foremost responsibility is the protection of our study participants health and wellbeing. Furthermore, all of our studies must undergo extensive review by a safety committee (known as the Institutional Review Board or IRB) prior to study start. The IRB, as well as the study sponsor, monitors safety data throughout the course of each study in the interest of protecting the rights and welfare of each study volunteer.

What is a research sponsor?

A sponsor is the company or organization that provides the protocols, medications, and financing needed to carry out the study.

What is a study protocol?

A study protocol is the document that describes the reasons why a study is being conducted, the study’s objectives, and the methods to be used when carrying out the clinical trial. MedVadis uses the information contained in the study protocol to conduct each trial in a scientifically valid and safe manner.

How long do the clinical trials last?

Clinical trials vary in length depending upon the treatment and condition being studied. Typically, most studies range from several weeks to a year in length. However trials involving progressive conditions such as Alzheimer’s disease can last longer.

How long is each study visit?

Initial evaluations are typically 2-3 hours in length during which time education regarding the study is provided, informed consent is obtained, and a comprehensive medical evaluation is performed. Subsequent visits are usually shorter and typically take only about an hour.

How frequent are the study visits?

Office visits are usually monthly but can range from weekly to quarterly. Telephone or telehealth visits may also occur during a study.

Will I need to stay overnight?

While MedVadis does conduct some studies that require overnight stays, the majority of our trials do not.

Can I withdraw before a trial ends?

Obtaining the information needed to determine whether a treatment should be approved for general use depends upon the completion of study treatment by the majority of enrolled participants. With that said, participation in a clinical research trial is always voluntary and study participants can withdraw from a trial at any time.

Will I receive compensation for participating in a research trial?

Sponsors provide research volunteers compensation for their time and travel associated with the study. Some study sponsors will also provide transportation to and from study appointments.

Will I receive medical care from MedVadis during the study?

MedVadis is a research center that conducts research trials according to the protocols established by the sponsors. Volunteers gain valuable information regarding their overall health from the comprehensive assessments performed during the study, however, medical treatments unrelated to the clinical trials are not provided. Your primary care physician and/or other physician specialists will need to provide any treatments needed beyond those offered in the study. With your permission, MedVadis will share health information with your physicians to facilitate your healthcare treatment.

What if I would like to volunteer but there isn’t a trial that I qualify for?

MedVadis continually evaluates and launches new research projects.  Please fill our contact information form and our staff will reach out to you when a trial relevant to your interests becomes available. Your information will only be used by MedVadis and will never be shared with others.

Where are you located?

MedVadis is located at Boston PainCare, 85 First Avenue, Waltham MA 02451. We are conveniently located just off route 128 and have ample free parking.

Is your office handicap accessible?

Yes, our office is wheelchair accessible. There is handicap parking adjacent to the main entrance.