Common symptoms of diabetic peripheral neuropathy include numbness, tingling, weakness, and cramping. Pain is also common, with up to 20% of diabetic experiencing symptoms of burning, hypersensitivity to touch and/or painful numbness. For some diabetics the symptoms of peripheral neuropathy can be quite severe, and can result in difficulties performing simple everyday tasks like walking and sleeping.
While the causes of diabetic peripheral neuropathy are not entirely known, high blood sugar levels are thought to play an important role in its development. Elevated levels of fat in the blood have also been shown to increase the risk for developing peripheral neuropathy. The symptoms of peripheral neuropathy can result from direct damage to the nerve fibers by the elevated levels of blood sugar and fat. Additionally, high blood sugar and fat levels can damage the blood vessels that surround and nourish nerves thus starving them of oxygen and nutrients.
Although diabetic neuropathy can occur in both type 1 and type 2 diabetes, it is more commonly seen in patients with type 2 diabetes. Tight glucose control can help slow the progression of nerve damage and may even improve nerve function in some cases. It is also important to note that tight glucose control alone may not be sufficient to prevent or reverse PDN in some cases, and other treatments may be needed to manage the symptoms of PDN.
We're conducting diabetic neuropathy clinical trials that could help us unlock new non-opioid treatments that may reduce symptoms of neuropathic pain, improve function and ultimately change lives. If your symptoms of diabetic peripheral neuropathy are poorly managed, then volunteering for one of our diabetic peripheral neuropathy clinical trials can be a way to access new and potentially more effective treatment options. Plus, it's a great way to give back; contribute to medical knowledge & have your voice heard all at once!
Don't wait – join our diabetic peripheral neuropathy research community and explore new treatment therapies today!
Healthcare insurance is not required and you may be reimbursed for your time.